WebAug 20, 2024 · The direct enantioselective 1,4- and 1,8-arylations of 7-methide-7H-indoles and 6-methide-6H-indoles, respectively, generated in situ from diarylmethanols, with electron-rich arenes as nucleophiles, has been achieved in the presence of chiral phosphoric acids (CPAs). WebJun 9, 2004 · A new chiral ammonium bromide, 1-Br, possessing diarylmethanol functionality as a substrate recognition site has been designed as a promising, dual-functioning catalyst for the highly enantioselective epoxidation of alpha,beta-unsaturated ketones under mild phase-transfer conditions. For instance, vigorous stirring of a mixture …
Silyl ether synthesis by silylation or cyanosilylation - Organic …
WebJan 17, 2007 · The preparation of diarylmethanol 7 and subsequent conversion into acetate 2 required carefully selected workups, selective extractions, and azeotropic distillations to generate a series of stock solutions to accommodate oil intermediates that finally gave acetate 2 as a crystalline solid with >99% ee. Supporting Information Available WebUltimately, a one-pot chemoenzymatic synthesis of enantioenriched alcohols was achieved through the combined use of nickel and biocatalysis in collaboration with Codexis. 92 For example,... how far is bay pines from tampa fl
Rational design of 1,2,3-triazole hybrid structures as novel …
WebFeb 1, 2024 · The use of diarylmethanols was next examined as we expected that the addition of a second aryl group would further stabilize the carbocation and thus favour ionization over the undesired reaction of the intermediate with residual starting material. WebFeb 7, 2024 · Corresponding Author. Katsuyuki Hirai. [email protected]; Department of Chemistry for Materials, Graduate School of Engineering, Mie University, Tsu, Mie, Japan WebJun 9, 2014 · A palladium-catalyzed cross-coupling reaction of diarylmethanol derivatives with diborylmethane has been developed. The reaction proceeds chemoselectively to deliver the corresponding homobenzylic ... hifish官网