WebFeb 22, 2024 · Phenytoin is a drug more commonly used in the treatment of epilepsy, but may play an important role in accelerating ulcer healing. Objectives: To assess the … WebApr 11, 2024 · Phenytoin is an example of repositioned drug investigated for diabetic wound healing, which was found to promote collagen deposition and increase re-epithelialization [ 9, 11 ]. Phenytoin (PHT) was brought to the market in 1938 as an antiepileptic drug.
Topical Phenytoin - Everwell
WebAug 6, 2024 · Systemically healthy adults were recruited. One 6 mm diameter wound (posterior) and one 4 mm diameter wound (anterior), each 1-1.5 mm deep, were created on both sides of the palate. Wounds on one randomly chosen side received 10% phenytoin USP and contralateral wounds received carrier alone. WebAug 24, 2010 · Topical phenytoin can enhance wound healing in recalcitrant neuropathic diabetic foot ulcers of patients with no clinical evidence of ischaemia or infection . In this study, the cream was used as a vehicle for the preparation of 0.5% topical phenytoin, and the vehicle cream was the control for the study, constantly hydrating the wound to avoid ... sqlite case with like
Topical (applied to the skin) phenytoin for treating
WebOver 60 years investigators have shown an interest in how topical phenytoin may be used to promote wound healing in a variety of chronic wounds. OBJECTIVES: Systematically to … WebJul 16, 2015 · Many topical agents have been used for promotion of healing of chronic venous ulcers. One such agent that has been tried is phenytoin. The effect of phenytoin on cutaneous healing has been... WebAug 1, 2024 · For several disorders, phenytoin is still undergoing some form of innovation, including for bipolar disorder and wound healing, amongst others (Keppel Hesselink, 2024 ). Using meta-analysis, it has also been revealed that phenytoin may be used to manage different types of ulcers ( Thangaraju et al., 2015). sqlite check if entry exists